6-(5-chloropyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione - Names and Identifiers
Name | 6-(5-chloro-2-pyridyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione
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Synonyms | ZOPE -INTG 7(6H)-dione 4-b]pyrazine-5 Right zopiclone impurity 8 Intermediate for Zopiclone I 6-(5-Chloro-2-pyridyl)-5H-pyrrolo[3 6-(5-chloropyridin-2-yl)pyrrolo[3,4-b]pyrazine-5,7-dione 6-(5-chloro-2-pyridyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione 6-(5-Chloro-2-pyridyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione 6-(5-Chloro-2-pyridyl)-5H-pyrrolo(3,4-b)pyrazine-5,7(6H)-dione 6-(5-Chloro-2-pyridinyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione 6-(5-chloropyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione
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CAS | 43200-82-4
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EINECS | 256-141-5 |
InChI | InChI=1/C11H5ClN4O2/c12-6-1-2-7(15-5-6)16-10(17)8-9(11(16)18)14-4-3-13-8/h1-5H |
6-(5-chloropyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione - Physico-chemical Properties
Molecular Formula | C11H5ClN4O2
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Molar Mass | 260.64 |
Density | 1.645±0.06 g/cm3(Predicted) |
Melting Point | 238 °C |
Boling Point | 495.7±55.0 °C(Predicted) |
Flash Point | 253.6°C |
Vapor Presure | 5.77E-10mmHg at 25°C |
pKa | -0.63±0.29(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.7 |
6-(5-chloropyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione - Introduction
6-(5-chloro-2-pyridyl)-5H-pyrirolo [3,4-b]pyrazine-5,7(6H)-dione is an organic compound with the chemical formula C11H5ClN4O2 and a molecular weight of 258.64g/mol.
The compound has the following properties:
-Appearance: White or light yellow solid
-Solubility: Slightly soluble in organic solvents, such as chloroform, dimethylformamide, difficult to dissolve in water
-Melting point: about 235~240°C
6-(5-chroo-2-pyridyl)-5H-pyrirolo [3,4-b]pyrazine-5,7(6H)-dione has certain application value in the field of drugs, mainly for the synthesis of bioactive molecules and drug candidate compounds. It is widely used in drug research, drug synthesis and drug screening.
The compound can be prepared by the following steps:
1. an appropriate amount of 5-chloro -2-pyridine amine and an appropriate amount of 2,3-ketone in the role of acid catalyst reaction, 5-(2,3-O) pyridine.
2. lithiation reaction of the product obtained in step 1 and 2,3-pyranedione to give 6-(5-chloro-2-pyridyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione.
Due to the lack of specific safety information, safety risks need to be evaluated and controlled according to specific uses and occasions. When handling and using the compound, relevant safe operating procedures should be observed, such as wearing appropriate protective equipment, ensuring good ventilation, and avoiding contact with skin, eyes and respiratory tract. At the same time, comply with local laws and regulations, and properly dispose of waste. Carefully study and understand the safety information of the above compounds before conducting any experiments.
Last Update:2024-04-09 21:11:58